A CV needs to be something that makes me stand out, and ultimately makes a potential employer be interested in what I produce. Without looking at my work beforehand, making a first impression that will stick with them, making them want to see my online portfolio, website or blog. I found some particularly good examples of presenting work in an original way.
I found a website designer, who uses flash to present his work, which also includes photography and some samples of his work. The website flows so fluidly, with a mini news feed, similar to a blog which he uses to keep you updated on what he is up to.
The most credible of his talents is how organic everything feels, even the transition between the numerous animations needed to go through before you get to his work makes the task of looking through his work really entertaining.
The websites he designs are interactive and seem quite tech, but the way his work is presented, such as the picture viewers he designed would be a perfect way to present a portfolio.
Here are some examples of good online portfolio's he has.
Banners - Left Aligned
http://www.murphycobb.com/
http://www.ev2.co.uk/ev2.html
http://www.a-to-s.co.uk/home.php
Another brilliant example of presenting work in a no-nonsense format is Designer Ben Barry,
using navigation techniques to help narrow down your viewing selection. The design of the folio lends itself to the size also, by clicking the icons, it highlights the sort of work you wish to view. This would come in handy, especially when needing to quickly present your work to a client, or to an employer.